منابع مشابه
Innexin Function: Minding the Gap Junction
Gap junctions mediate intercellular communication and are critical for development and nervous system function. Initially thought to function solely as stand-alone molecules, it has now been shown that a stomatin-like protein regulates a gap junction channel in Caenorhabditis elegans.
متن کاملMinding the gap.
T he ECWA Eye Hospital in Kano, Nigeria, is a mission hospital started by Dr Hursch, an American ophthalmologist, in the early 1940s. Although there are no surviving records from the time of Dr Hursch, I would venture to say that his practice of ophthalmology in Nigeria was not much different from his practice in America. Since the cutting edge tools of his day were loupes, and a small set of i...
متن کاملMinding the Gap
I'm all for pragmatics. But I don't think it helps the cause to blur the boundary between semantics and pragmatics. The purpose of this chapter is to explain why. The basic reason is this. Even though, as people have been pointing out for some years now, the linguistic meaning of a given sentence generally underdetermines what a speaker means in uttering it, it does not follow that linguistic m...
متن کاملThe Drosophila gap junction channel gene innexin 2 controls foregut development in response to Wingless signalling.
In invertebrates, the direct communication of neighbouring cells is mediated by gap junctions, which are composed of oligomers of the innexin family of transmembrane proteins. Studies of the few known innexin mutants in Drosophila and C. elegans have shown that innexin proteins, which are structurally analogous to the connexins in vertebrates, play a major structural role as gap junctional core...
متن کاملGap junction channel protein innexin 2 is essential for epithelial morphogenesis in the Drosophila embryo.
Direct communication of neighboring cells by gap junction channels is essential for the development of tissues and organs in the body. Whereas vertebrate gap junctions are composed of members of the connexin family of transmembrane proteins, in invertebrates gap junctions consist of Innexin channel proteins. Innexins display very low sequence homology to connexins. In addition, very little is k...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2007
ISSN: 0960-9822
DOI: 10.1016/j.cub.2007.07.043